sivic open-source software Search Results


crl  (ATCC)
96
ATCC crl
Crl, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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sivic open-source software  (SourceForge net)
90
SourceForge net sivic open-source software
Sivic Open Source Software, supplied by SourceForge net, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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siv ic  (SourceForge net)
90
SourceForge net siv ic
Siv Ic, supplied by SourceForge net, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/siv ic/product/SourceForge net
Average 90 stars, based on 1 article reviews
siv ic - by Bioz Stars, 2026-03
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idl  (Exelis Visual Information Solutions Inc)
90
Exelis Visual Information Solutions Inc idl
Idl, supplied by Exelis Visual Information Solutions Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/idl/product/Exelis Visual Information Solutions Inc
Average 90 stars, based on 1 article reviews
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masshunter vistaflux  (Agilent technologies)
90
Agilent technologies masshunter vistaflux
Key Resources Table
Masshunter Vistaflux, supplied by Agilent technologies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
masshunter vistaflux - by Bioz Stars, 2026-03
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d 5 ]-2-hydroxuglutarate  (Millipore)
90
Millipore d 5 ]-2-hydroxuglutarate
Key Resources Table
D 5 ] 2 Hydroxuglutarate, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/d 5 ]-2-hydroxuglutarate/product/Millipore
Average 90 stars, based on 1 article reviews
d 5 ]-2-hydroxuglutarate - by Bioz Stars, 2026-03
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4,4-dimethyl-4-silapentane-1-sulfonic acid  (Millipore)
90
Millipore 4,4-dimethyl-4-silapentane-1-sulfonic acid
A and B IC50 plot of JJ012 and CS1 cells respectively, grown in media supplemented with 5 mM glutamine and increasing concentrations of IDH1 inhibitor (IDHi) <t>AGI-5198.</t> JJ012 cells show sensitivity to the drug, with a maximum inhibition of 2-HG production of approximately 90%. CS1 cells show limited sensitivity to AGI-5198. C and D Isotopic enrichment in JJ012 cells incubated with [13C5] Gln without (control) or with (IDHi) 2 µM of IDHi demonstrates the glutamate pool is unchanged by inhibition of mutant IDH1 while the apparent rate of 2-HG production is reduced as a function of total 2-HG pools. Data are representative of mean ± S.D. of 3 replicates from 3 experiments carried independently.
4,4 Dimethyl 4 Silapentane 1 Sulfonic Acid, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/4,4-dimethyl-4-silapentane-1-sulfonic acid/product/Millipore
Average 90 stars, based on 1 article reviews
4,4-dimethyl-4-silapentane-1-sulfonic acid - by Bioz Stars, 2026-03
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crl 1420 hpac atcc  (ATCC)
99
ATCC crl 1420 hpac atcc
A and B IC50 plot of JJ012 and CS1 cells respectively, grown in media supplemented with 5 mM glutamine and increasing concentrations of IDH1 inhibitor (IDHi) <t>AGI-5198.</t> JJ012 cells show sensitivity to the drug, with a maximum inhibition of 2-HG production of approximately 90%. CS1 cells show limited sensitivity to AGI-5198. C and D Isotopic enrichment in JJ012 cells incubated with [13C5] Gln without (control) or with (IDHi) 2 µM of IDHi demonstrates the glutamate pool is unchanged by inhibition of mutant IDH1 while the apparent rate of 2-HG production is reduced as a function of total 2-HG pools. Data are representative of mean ± S.D. of 3 replicates from 3 experiments carried independently.
Crl 1420 Hpac Atcc, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Key Resources Table

Journal: Cell metabolism

Article Title: In vivo imaging of glutamine metabolism to the oncometabolite 2-hydroxyglutarate in IDH1/2 mutant tumors

doi: 10.1016/j.cmet.2017.10.001

Figure Lengend Snippet: Key Resources Table

Article Snippet: ​ REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals [1- 13 C] Glutamine Sigma Cat # 605018 OX063 Oxford Chemicals N/A [ 13 C 5 ] glutamine Sigma Cat # 605166 [d 5 ]-2-hydroxuglutarate Sigma Cat # 16059 [ 13 C 6 ] Glucose Sigma Cat # 389374 [5- 13 C, 15 N] glutamine Sigma Cat # 607983 AGI-5198 Agios N/A 4,4-dimethyl-4-silapentane-1-sulfonic acid Sigma Cat # 613150 Gd-DOTA Biocyclics Cat # M-147 Experimental Models: Cell Lines JJ012 MSKCC N/A CS1 MSKCC N/A MiaPaCa-2 ATCC Cat # CRL-1420 HPAC ATCC Cat # CRL-2119 Experimental Models: Organisms/Strains Mice strain NOD.Cg-Prkdc scid Il2rg tm1Wjl /SzJ Jackson Laboratory Cat # 005557 Software and Algorithms Prism Graphpad https://www.graphpad.com/scientific-software/prism/ Osirix Osirix http://www.osirix-viewer.com/ SIVIC Sourceforge https://sourceforge.net/projects/sivic/ MATLAB Mathworks https://www.mathworks.com/ Chenomx ChenomX http://www.chenomx.com/ Xcalibur Thermo Scientific https://www.thermofisher.com/order/catalog/product/OPTON-30487 TraceFinder Thermo Scientific https://www.thermofisher.com/order/catalog/product/OPTON-30491 Nanoscan Mediso N/A SpinSolve Magritek http://www.magritek.com MassHunter VistaFlux Agilent N/A MassHunter Quant Agilent N/A Open in a separate window Key Resources Table Glutamine is a primary carbon source for the oncometabolite 2-hydroxyglutarate.

Techniques: Software

A and B IC50 plot of JJ012 and CS1 cells respectively, grown in media supplemented with 5 mM glutamine and increasing concentrations of IDH1 inhibitor (IDHi) AGI-5198. JJ012 cells show sensitivity to the drug, with a maximum inhibition of 2-HG production of approximately 90%. CS1 cells show limited sensitivity to AGI-5198. C and D Isotopic enrichment in JJ012 cells incubated with [13C5] Gln without (control) or with (IDHi) 2 µM of IDHi demonstrates the glutamate pool is unchanged by inhibition of mutant IDH1 while the apparent rate of 2-HG production is reduced as a function of total 2-HG pools. Data are representative of mean ± S.D. of 3 replicates from 3 experiments carried independently.

Journal: Cell metabolism

Article Title: In vivo imaging of glutamine metabolism to the oncometabolite 2-hydroxyglutarate in IDH1/2 mutant tumors

doi: 10.1016/j.cmet.2017.10.001

Figure Lengend Snippet: A and B IC50 plot of JJ012 and CS1 cells respectively, grown in media supplemented with 5 mM glutamine and increasing concentrations of IDH1 inhibitor (IDHi) AGI-5198. JJ012 cells show sensitivity to the drug, with a maximum inhibition of 2-HG production of approximately 90%. CS1 cells show limited sensitivity to AGI-5198. C and D Isotopic enrichment in JJ012 cells incubated with [13C5] Gln without (control) or with (IDHi) 2 µM of IDHi demonstrates the glutamate pool is unchanged by inhibition of mutant IDH1 while the apparent rate of 2-HG production is reduced as a function of total 2-HG pools. Data are representative of mean ± S.D. of 3 replicates from 3 experiments carried independently.

Article Snippet: ​ REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals [1- 13 C] Glutamine Sigma Cat # 605018 OX063 Oxford Chemicals N/A [ 13 C 5 ] glutamine Sigma Cat # 605166 [d 5 ]-2-hydroxuglutarate Sigma Cat # 16059 [ 13 C 6 ] Glucose Sigma Cat # 389374 [5- 13 C, 15 N] glutamine Sigma Cat # 607983 AGI-5198 Agios N/A 4,4-dimethyl-4-silapentane-1-sulfonic acid Sigma Cat # 613150 Gd-DOTA Biocyclics Cat # M-147 Experimental Models: Cell Lines JJ012 MSKCC N/A CS1 MSKCC N/A MiaPaCa-2 ATCC Cat # CRL-1420 HPAC ATCC Cat # CRL-2119 Experimental Models: Organisms/Strains Mice strain NOD.Cg-Prkdc scid Il2rg tm1Wjl /SzJ Jackson Laboratory Cat # 005557 Software and Algorithms Prism Graphpad https://www.graphpad.com/scientific-software/prism/ Osirix Osirix http://www.osirix-viewer.com/ SIVIC Sourceforge https://sourceforge.net/projects/sivic/ MATLAB Mathworks https://www.mathworks.com/ Chenomx ChenomX http://www.chenomx.com/ Xcalibur Thermo Scientific https://www.thermofisher.com/order/catalog/product/OPTON-30487 TraceFinder Thermo Scientific https://www.thermofisher.com/order/catalog/product/OPTON-30491 Nanoscan Mediso N/A SpinSolve Magritek http://www.magritek.com MassHunter VistaFlux Agilent N/A MassHunter Quant Agilent N/A Open in a separate window Key Resources Table Glutamine is a primary carbon source for the oncometabolite 2-hydroxyglutarate.

Techniques: Inhibition, Incubation, Mutagenesis